Clinical Trial Design for Orphan Drugs: Unique Challenges and Solutions
Clinical trial design for orphan drugs presents unique challenges due to the small patient populations and limited data available. One of the key challenges is identifying and recruiting enough eligible patients for the trial. In addition, determining the appropriate endpoints and outcome measures can be difficult, as the natural history of the disease may not be well understood. Solutions to these challenges include the use of adaptive trial designs, innovative statistical methods, and collaboration between multiple stakeholders, including patient advocacy groups and regulatory agencies. Furthermore, the use of surrogate endpoints and patient-reported outcomes can provide valuable information when traditional endpoints are not feasible. Overall, successful clinical trial design for orphan drugs requires a tailored and collaborative approach that addresses the unique challenges faced in this field.
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Clinical Trial Design for Orphan Drugs: Unique Challenges and Solutions Conference Speakers
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